← ingredient library
BrighteningSebum RegulatorAnti-inflammatoryBarrier Repair

Niacinamide

🏆 hero ingredient Tier 1 Evidence

what it does

A form of vitamin B3 that regulates sebum production, fades hyperpigmentation, strengthens the skin barrier, and calms redness. One of the most versatile and well-tolerated skincare actives.

dermai take

The main character of your entire routine. Does like five jobs at once — brighten, calm, regulate oil, fix your barrier — plays nice with almost everything, and doesn't throw a fit on sensitive skin. Genuine GOAT of skincare.

targets these concerns

AcneHyperpigmentationPoresOilinessSensitivityRosaceaSun Damage

don't combine with

Vitamin Clow

Historically thought to cause flushing (nicotinic acid formation), but modern stable formulations show minimal interaction. Low concern.

💡 Generally safe together. Separate by 30 min if you notice any flushing.

the studies

"Niacinamide: A B vitamin that improves aging facial skin appearance."
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (2005) · Bissett DL, Oblong JE, Berge CA
"The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer."
The British journal of dermatology (2002) · Hakozaki T, Minwalla L, Zhuang J et al.

products with this ingredient

Toleriane Hydrating Gentle CleanserLa Roche-Posay